Addition of acrylamide to amino aldehydes to generate non-Baylis-Hillman adducts. Formation of novel N-acylhemiaminals

DOI: 10.1246/cl.1998.787

Source and publish data:

Chemistry Letters p. 787 - 788 (1998)

Update date:2022-08-17

Topics:

Authors:

Bussolari, Jacqueline C.

Beers, Kimberly

Lalan, Praful

Murray, William V.

Gauthier, Diane

McDonnell, Patricia

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Article abstract of DOI:10.1246/cl.1998.787

Aldol reactions of chiral aminoaldehydes and methylacrylate in the presence of 1,4-diazabicyclo[2.2.2]octane (DABCO) produces β-hydroxy methylbutenoates which can be utilized as psuedodipepetides. However, reaction of aminoaldehydes with acrylamide in the

Full text of DOI:10.1246/cl.1998.787

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