138944-41-9Relevant academic research and scientific papers
Synthesis of 6-methoxy- and 6-chloro-2(1H)-pyridinone acyclo-C-nucleosides from 2H-1,4-oxazin-2-ones
Meerpoel, Lieven,Joly, Gert J.,Hoornaert, Georges J.
, p. 4085 - 4098 (2007/10/02)
Starting from 6-variated 3-methoxy- and 3-chloro-2H-1,4-oxazin-2-ones 4a-e the synthesis of a series of 6-methoxy- and 6-chloro-2(1H)-pyridinone acyclo-C-nucleosides 2a-d and 3a-d was accomplished. Diels-Alder reaction of the oxazinones 4a-e with propargy
An approach to acyclo-1-deazathymidine c-nucleosides via 3,5-dichloro-6-methyl-2H-1,4-oxazin-2-one
Meerpoel, Lieven,Toppet, Suzanne M.,Compernolle, Frans,Hoornaert, Georges J.
, p. 10065 - 10076 (2007/10/02)
An approach to the synthesis of acyclo-1-deazathymidine nucleosides is described. Diels-Alder reaction of 3,5-dichloro-6-methyl-2H-1,4-oxazin-2-one with acetylenic compounds 4 and 5 yielded the 3-[(tetrahydropyran-2-yl)oxy]-methyl- and 3-bromomethyl-5-met
