138971-83-2

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 138971-82-1 (E)-2-(Benzhydrylidene-amino)-5-(1-benzyloxycarbonylmethyl-cyclohexyl)-pent-4-enoic acid ethyl ester 
• 138971-79-6 (E)-3-(1-Benzyloxycarbonylmethyl-cyclohexyl)-acrylic acid tert-butyl ester 
• 138971-76-3 3-(1-Benzyloxycarbonylmethyl-cyclohexyl)-propionic acid tert-butyl ester 
• 138990-48-4 (E)-3-(1-Benzyloxycarbonylmethyl-cyclohexyl)-acrylic acid 
• 113009-25-9 1,1,-Cyclohexanediacetic acid monobenzyl ester 
• 138971-80-9 [1-((E)-3-Hydroxy-propenyl)-cyclohexyl]-acetic acid benzyl ester 
• 138971-81-0 [1-((E)-3-Iodo-propenyl)-cyclohexyl]-acetic acid benzyl ester 
• 138971-75-2 3-(1-Carboxymethyl-cyclohexyl)-propionic acid tert-butyl ester 
• 138971-78-5 (3-Oxo-2-oxa-spiro[4.5]dec-1-yl)-acetic acid tert-butyl ester 

Downstream Products

• 138971-84-3 (E)-5-(1-Benzyloxycarbonylmethyl-cyclohexyl)-2-tert-butoxycarbonylamino-pent-4-enoic acid 

Relevant academic research and scientific papers

A trans olefin replacement of the disulfide bridge found in cyclic peptides: Synthesis of 6,6-pentamethylene-2-amino-Δ4,5-suberic acid

Substitution of the sulfur atoms in the disulfide bridge of cyclic peptides with a trans olefin incorporates the features of a dicarba replacement while introducing a greater torsional restriction. The synthesis of the differentially protected racemic 6,6