138971-80-9Relevant academic research and scientific papers
A trans olefin replacement of the disulfide bridge found in cyclic peptides: Synthesis of 6,6-pentamethylene-2-amino-Δ4,5-suberic acid
Callahan,Newlander,Huffman
, p. 7203 - 7206 (2007/10/02)
Substitution of the sulfur atoms in the disulfide bridge of cyclic peptides with a trans olefin incorporates the features of a dicarba replacement while introducing a greater torsional restriction. The synthesis of the differentially protected racemic 6,6
