139-25-3

Usage

Uses

Used in Polyurethane Industry:
4,4'-Diisocyanato-3,3'-dimethyldiphenylmethane is used as a key chemical intermediate for the production of polyurethane materials. It serves as a crucial component in the synthesis of rigid and flexible polyurethane foams, which are widely used in various applications such as insulation materials, furniture, bedding, automotive components, and construction materials. The high reactivity and thermal stability of MDI contribute to the excellent performance and durability of the resulting polyurethane products.
Used in Environmental Monitoring:
4,4'-Diisocyanato-3,3'-dimethyldiphenylmethane is also recognized as an environmental toxin and is listed on the US Environmental Protection Agency (EPA) Toxic Release Inventory (TRI) list. This listing highlights the need for proper handling, storage, and disposal of MDI to minimize its potential impact on human health and the environment. Industries that use MDI in their manufacturing processes are required to report their releases of this chemical to the EPA, allowing for better tracking and management of its environmental risks.

Reactivity Profile

Isocyanates and thioisocyanates, such as 4,4'-DIISOCYANATO-3,3'-DIMETHYLDIPHENYLMETHANE, are incompatible with many classes of compounds, reacting exothermically to release toxic gases. Reactions with amines, aldehydes, alcohols, alkali metals, ketones, mercaptans, strong oxidizers, hydrides, phenols, and peroxides can cause vigorous releases of heat. Acids and bases initiate polymerization reactions in these materials. Some isocyanates react with water to form amines and liberate carbon dioxide. Base-catalysed reactions of isocyanates with alcohols should be carried out in inert solvents. Such reactions in the absence of solvents often occur with explosive violence, [Wischmeyer(1969)].

Safety Profile

Poison by intravenous route. A sensitizer. When heated to decomposition it emits toxic fumes of NOx and CN-.

Upstream product

• 75-44-5 phosgene 
• 838-88-0 3,3'-dimethyl-4,4'-diaminodiphenylmethane 

Downstream Products

• 59255-83-3 C₂₇H₃₈N₂O₄ 

Relevant academic research and scientific papers

Hydrolytically degradable polyester/silicon co-crosslinked matrices

Polyester/silicon co-crosslinked polymer substrates at least partially degradable by hydrolysis, well adopted as matrices for the controlled release of a wide variety of active agents therefrom, are prepared by controlledly co-crosslinking (a) at least one diorganopolysiloxane having at least two hydroxyl groups per molecule and (b) an oligomeric polylactic and/or polyglycolic polyester α,ω-diol, with an effective co-crosslinking amount of (c) an organic polyisocyanate.

METHOD OF PRODUCING MODIFIED ORGANIC POLYISOCYANATE

A modified organic polyisocyanate having isocyanurate rings is produced by adding a trimerization catalyst, an organic phosphite, a surfactant and, if desired, a ferrocene compound to an organic polyisocyanate and/or partially urethanated organic polyisocyanate, converting at most 20 % by weight of all of the isocyanate groups into isocyanurate groups, and adding, if necessary, a terminating agent to the reaction system.

Ethylenic silicon compounds and thermoplastic elastomers obtained therefrom

The invention provides organosilicon compounds of the formula: STR1 in which: N IS 1, 2 OR 3; Each R, which may be identical or different, is a monovalent organic group which contains a carbon-carbon double bond and from 2 to 10 carbon atoms; Each R1, which may be identical or different, is a straight or branched alkyl radical optionally substituted by one or more halogen atoms or cyano groups; an aryl radical or an alkylaryl radical optionally substituted by one or more halogen atoms; R2 is a straight or branched divalent alkylene or alkylidene radical possessing up to 4 carbon atoms; X is a divalent radical consisting of, or containing, at least one hetero-atom selected from oxygen, sulphur and nitrogen atoms, the radical being attached to the radical R2 via a said hetero-atom; G is an organic radical of valency (m+ l) possess from 1 to 30 carbon atoms; m is 1, 2 or 3; And each Y, which may be identical or different, is a functional group selected from: --NO2, STR2 --COOM (where M represents a sodium, potassium or lithium atom); --COOR4 ; STR3 --COCl; --OH; --OR4 ; STR4 --SH; --SR4 ; STR5 --CONH2 ; --CSNH2 ; --CN; --CH2 --NH2 ; --CHO; STR6 --NCO; STR7 wherein R3 represents a hydrogen atom or a straight or branched alkyl radical possessing up to 6 carbon atoms and R4 represents an alkyl radical possessing up to 4 carbon atoms, with the proviso that two Y groups can together constitute an imide group STR8 wherein R5 represents a hydrogen atom or a straight or branched alkyl radical possessing up to 4 carbon atoms. These are useful intermediates in the preparation of disilanes and silicon polymers, in particular of polyethylenic silicon compounds which can be polymerized with an α, ω-dihydrogenopolysiloxane to give thermoplastic elastomers.