139003-86-4Relevant articles and documents
TIN (IV) CHLORIDE-PROMOTED REACTIONS OF α-HYDROXY NITRILES WITH β-DICARBONYL COMPOUNDS. SYNTHESIS OF 4-AMINO-2,5-DIHYDRO-2-FURANONES AND THEIR CONVERSION INTO TETRONIC ACID DERIVATIVES
Veronese, Augusto C.,Callegari, Rosella,Bertazzo, Antonella
, p. 2205 - 2215 (2007/10/02)
β-Keto esters and β-diesters react with α-hydroxy nitriles in the presence of stoichiometric amounts of tin(IV) chloride to give 3-acyl-4-amino-2(5H)-furanones (2) and ethyl 4-amino-2,5-dihydro-2-oxofuran-3-carboxylates (3).The acyldihydrofuranones (2) can be converted into acyltetronic acid derivatives (6) while the ethyl furan-3-carboxylates (3) can be converted into tetronic acids (8).
