139004-96-9

Basic information

• Product Name: (R)-PIPERIDIN-2-YLMETHYL-CARBAMIC ACID TERT-BUTYL ESTER
• Synonyms: (R)-PIPERIDIN-2-YLMETHYL-CARBAMIC ACID TERT-BUTYL ESTER;(R)-2-Boc-Aminomethylpiperidine hydrochloride;(R)-Piperidin-2-ylmethylcarbamic acid tert-butyl ester hydrochloride;Carbamic acid, (2-piperidinylmethyl)-, 1,1-dimethylethyl ester, (R)- (9CI);(R)-tert-butyl piperidin-2-ylmethylcarbamate hydrochloride;R-2-BOC-AMINOMETHYL-PIPERIDINE-HCl;(R)-tert-Butyl (piperidin-2-ylMethyl)carbaMate;CarbaMic acid, N-[(2R)-2-piperidinylMethyl]-, 1,1-diMethylethyl ester
• CAS NO: 139004-96-9
• Molecular Formula: C₁₁H₂₂N₂O₂
• Molecular Weight: 250.77
• Mol File: 139004-96-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 287.9°C at 760 mmHg
• Flash Point: 127.9°C
• Appearance: /
• Density: 1.01g/cm³
• Vapor Pressure: 0.00242mmHg at 25°C
• Refractive Index: 1.485
• Storage Temp.: 2-8°C
• PKA: 12.84±0.46(Predicted)
• CAS DataBase Reference: (R)-PIPERIDIN-2-YLMETHYL-CARBAMIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-PIPERIDIN-2-YLMETHYL-CARBAMIC ACID TERT-BUTYL ESTER(139004-96-9)
• EPA Substance Registry System: (R)-PIPERIDIN-2-YLMETHYL-CARBAMIC ACID TERT-BUTYL ESTER(139004-96-9)

Safety Data

• Hazardous Substances Data: 139004-96-9(Hazardous Substances Data)

Usage

Uses

Chiral building block developed using Liverpool ChiroChem-patented technology.

InChI:InChI=1/C11H22N2O2/c1-11(2,3)15-10(14)13(4)9-7-5-6-8-12-9/h9,12H,5-8H2,1-4H3

Upstream product

• 1723-00-8 (R)-(+)-pipecolic acid 
• 139004-94-7 (R)-1-Benzyl-piperidine-2-carboxylic acid amide 
• 19889-77-1 (+)-2R-Piperidine-2-carboxylic acid amide 
• 18650-38-9 (R)-piperidine-2-carboxylic acid methyl ester hydrochloride 
• 139004-95-8 C-((R)-1-Benzyl-piperidin-2-yl)-methylamine 

Downstream Products

• 1314605-40-7 C₂₇H₃₅BrN₄O 

Relevant articles and documents

Synthesis of (D)- And (L)-forms of differentially protected 2-piperidinemethanamine

(D)- and (L)-isomers of pipecolic acid were converted into (D)- and (L)-2-piperidinemethanamine using an efficient sequence. The amino groups were selectively protected for further functionalization.