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1-(2-chloroethyl)-3-(4-chlorophenyl)-1-nitrosourea, commonly known as CCNU, is a nitrosourea alkylating agent characterized by its potent anticancer properties. It is derived from the nitrosourea class of compounds, which are known for their ability to alkylate and cross-link DNA, thereby disrupting the replication process in cancer cells and leading to cell death. CCNU is a highly potent and toxic chemical, necessitating careful administration and monitoring due to its potential for severe side effects.

13907-78-3

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13907-78-3 Usage

Uses

Used in Anticancer Applications:
CCNU is utilized as a chemotherapy agent for the treatment of various types of cancer, including brain tumors, lymphoma, and multiple myeloma. It functions by interfering with the DNA replication process in cancer cells, which results in their death. Despite its toxicity and potential for serious side effects, such as bone marrow suppression, gastrointestinal issues, and liver toxicity, CCNU has demonstrated efficacy in the treatment of certain cancers and remains a crucial component of chemotherapy protocols for these diseases.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, CCNU is used as a key component in the development of cancer treatment regimens. Its potent alkylating properties make it a valuable asset in the fight against cancer, particularly for aggressive and hard-to-treat malignancies. However, due to its toxicity, the development of novel drug delivery systems and combination therapies is essential to enhance its safety profile and therapeutic outcomes.
Used in Research and Development:
CCNU is also employed in research and development settings to study the mechanisms of action of nitrosourea compounds and their potential applications in cancer treatment. This includes investigating the effects of CCNU on DNA replication, cellular metabolism, and the development of drug resistance in cancer cells. Additionally, research into the optimization of CCNU's administration and dosage, as well as the development of less toxic analogs, is ongoing to improve its clinical utility and patient outcomes.

Check Digit Verification of cas no

The CAS Registry Mumber 13907-78-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,9,0 and 7 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 13907-78:
(7*1)+(6*3)+(5*9)+(4*0)+(3*7)+(2*7)+(1*8)=113
113 % 10 = 3
So 13907-78-3 is a valid CAS Registry Number.

13907-78-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2-chloroethyl)-3-(4-chlorophenyl)-1-nitrosourea

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
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More Details:13907-78-3 SDS

13907-78-3Downstream Products

13907-78-3Relevant academic research and scientific papers

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