65536-39-2

Usage

Uses

Used in Agricultural Industry:
1-(2-chloroethyl)-3-(4-chlorophenyl)urea is used as a herbicide for controlling broadleaf weeds in agricultural settings. Its selective action on these weeds, while sparing grasses, makes it an effective and efficient solution for weed management in various crops.
Used in Industrial Settings:
In industrial settings, 1-(2-chloroethyl)-3-(4-chlorophenyl)urea is used as a herbicide to manage weed growth in areas such as storage facilities, manufacturing plants, and other non-agricultural lands. Its ability to inhibit the growth of weeds and disrupt their biochemical processes ensures a clean and well-maintained environment.
1-(2-chloroethyl)-3-(4-chlorophenyl)urea works by targeting the cellular processes of broadleaf weeds, ultimately leading to their death. This makes 1-(2-chloroethyl)-3-(4-chlorophenyl)urea a valuable tool in the fight against unwanted vegetation in both agricultural and industrial applications.

Upstream product

• 1943-83-5 2-chloroethyl isothiocyanate 
• 106-47-8 4-chloro-aniline 
• 20729-41-3 acetaldehyde imine 
• 104-12-1 p-chlorphenylisocyanate 

Downstream Products

• 1848-67-5 2-(4-Chlor-anilino)-2-oxazolin 
• 66671-20-3 N-(4-chloro-phenyl)-N'-(2-hydroxy-ethyl)-urea 
• 1169705-55-8 (3-{5-[3-(4-chloro-phenyl)-2-thioxo-imidazolidin-1-yl]-pentyloxy}-phenyl)-thiourea 
• 1169705-54-7 (3-{5-[3-(4-chloro-phenyl)-2-oxo-imidazolidin-1-yl]-pentyloxy}-phenyl)-thiourea 
• 14088-99-4 1-(4-chlorophenyl)-2-imidazolidinone 
• 13907-78-3 N-Nitroso-N-(2-chlor-aethyl)-N'-(4-chlor-phenyl)-harnstoff 

Relevant academic research and scientific papers

Design and efficient synthesis of novel arylthiourea derivatives as potent hepatitis C virus inhibitors

A novel class of arylthiourea HCV inhibitors bearing various functionalities, such as cyclic urea, cyclic thiourea, urea, and thiourea, on the alkyl linker were designed and synthesized. Herein we report the synthesis and structure-activity relationships

IMIDAZOLIDINONE AND IMIDAZOLIDINETHIONE DERIVATIVES

Imidazolidinone and imidazolinethione compounds of formula (I): wherein R1, R2, R3, A1, A2, X, Y, Z, m, n, p, x, and y are defined herein. Also disclosed is a method of treating hepatitis C virus infe

Antimitotic antitumor agents: Synthesis, structure-activity relationships, and biological characterization of N-aryl-N′-(2-chloroethyl)ureas as new selective alkylating agents

A series of N-aryl-N′-(2-chloroethyl)ureas (CEUs) and derivatives were synthesized and evaluated for antiproliferative activity against a wide panel of tumor cell lines. Systematic structure-activity relationship (SAR) studies indicated that: (i) a branched alkyl chain or a halogen at the 4-position of the phenyl ring or a fluorenyl/indanyl group, (ii) an exocyclic urea function, and (iii) a N′-2-chloroethyl moiety were required to ensure significant cytotoxicity. Biological experiments, such as immunofluorescence microscopy, confirmed that these promising compounds alter the cytoskeleton by inducing microtubule depolymerization via selective alkylation of β-tubulin. Subsequent evaluations demonstrated that potent CEUs were weak alkylators, were non-DNA-damaging agents, and did not interact with the thiol function of either glutathione or glutathione reductase. Therefore, CEUs are part of a new class of antimitotic agents. Finally, among the series of CEUs evaluated, compounds 12, 15, 16, and 27 were selected for further in vivo trials.

N-(Substituted)aminocarbonyl O,S-dialkyl phosphoramido(di)thioates and method of controlling arthropods

This invention relates to novel phosphoramido(di)thioates of the formula: STR1 wherein A is A. a halogen atom, B. a cyano group, C. a (C1 -C6) alkoxy group, D. a (C1 -C6) alkylthio group, E. a (C1 -C6) alkylcarbonyloxy group, F. a phenoxy group, or G. a phenylthio group; R1 is A. a (C1 -C12) alkyl group, B. a (C3 -C8) cycloalkyl group, C. an optionally substituted aralkyl group of up to 11 carbon atoms, or D. an optionally substituted (C6 -C10) aryl group; R2 is a hydrogen atom or a (C1 -C4) alkyl group when A is a halogen atom, and a hydrogen atom when A is other than a halogen atom; R3 is a (C1 -C6) alkyl group; R4 is a (C1 -C6) alkyl group; R5 and R6 are independently hydrogen atoms or (C1 -C4) alkyl groups; and Y is an oxygen or sulfur atom; To compositions containing them, to processes for preparing them, and to methods of utilizing them as arthropodicides.