139157-96-3Relevant academic research and scientific papers
Structure-activity studies of morphine fragments. III. Synthesis, opiate receptor binding, analgetic activity and conformational studies of spiro-[tetralin-1,4'-piperidines]
Lawson,Toll,Polgar,Uyeno,Loew
, p. 775 - 785 (1991)
A series of 5 spiro compounds, a new class of conformationally restricted analogs of 4-alkyl-4-(m-OH-phenyl) piperidines, have been synthesized and their affinities for μ, δ and κ opioid receptor sites and in vivo analgetic activities determined. All comp
