139163-60-3

Basic information

• Product Name: rac-2,2-dimethyl-1-<6-(2-methoxyphenyl)pyridin-2-yl>propanol
• Synonyms: rac-2,2-dimethyl-1-<6-(2-methoxyphenyl)pyridin-2-yl>propanol
• CAS NO: 139163-60-3
• Molecular Weight: 271.359
• Mol File: 139163-60-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: rac-2,2-dimethyl-1-<6-(2-methoxyphenyl)pyridin-2-yl>propanol(CAS DataBase Reference)
• NIST Chemistry Reference: rac-2,2-dimethyl-1-<6-(2-methoxyphenyl)pyridin-2-yl>propanol(139163-60-3)
• EPA Substance Registry System: rac-2,2-dimethyl-1-<6-(2-methoxyphenyl)pyridin-2-yl>propanol(139163-60-3)

Safety Data

• Hazardous Substances Data: 139163-60-3(Hazardous Substances Data)

Upstream product

• 5720-06-9 2-Methoxyphenylboronic acid 
• 127127-27-9 (rac)-1-(6-bromopyridin-2-yl)-2,2-dimethylpropan-1-ol 
• 630-19-3 pivalaldehyde 

Relevant articles and documents

Enantioselective Synthesis of Optically Active Pyridine Derivatives and C2-Symmetric 2,2'-Bipyridines

Optically active pyridine derivatives 2, 15, 18, 19, 21, 26, and 27 are obtained by enantioselective reduction of the corresponding ketones 5, 7, 11-13, 24, and 25 using the chiral borane reagent chlorodiisopinocampherylborane .Nickel(0)-mediated coupling of bromopyridines 2, 15, and 31 gives C2-symmetric 2,2'-bipyridines (R,R)-32, (R,R)-33, and (S,S)-38, respectively, which form metal complexex with Co(II), Pd(II), Cu(I), and Ag(I).Aryl-substituted pyridines 26, and 39-41 are synthesized by palladium(0)-catalized cross coupling of 2 and 15 with boronic acids 42-44.Key Words: 2,2-Bipyridines / Pyridines, optically active / Chiral ligands / Asymmetric Synthesis / Catalysis, enantioselective