1391630-42-4

Basic information

• Product Name: 2-[1-(4-methylphenylsulfonyl)-1H-indol-3-yl]N-(benzothiazol-2-yl)acetamide
• Synonyms: 2-[1-(4-methylphenylsulfonyl)-1H-indol-3-yl]N-(benzothiazol-2-yl)acetamide
• CAS NO: 1391630-42-4
• Molecular Weight: 461.565
• Mol File: 1391630-42-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[1-(4-methylphenylsulfonyl)-1H-indol-3-yl]N-(benzothiazol-2-yl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[1-(4-methylphenylsulfonyl)-1H-indol-3-yl]N-(benzothiazol-2-yl)acetamide(1391630-42-4)
• EPA Substance Registry System: 2-[1-(4-methylphenylsulfonyl)-1H-indol-3-yl]N-(benzothiazol-2-yl)acetamide(1391630-42-4)

Safety Data

• Hazardous Substances Data: 1391630-42-4(Hazardous Substances Data)

Upstream product

• 136-95-8 2-amino-benzthiazole 
• 128742-77-8 [N-(p-toluenesulfonyl)indol-3-yl]acetic acid 

Relevant articles and documents

Synthesis and biological evaluation of benzothiazole incorporated 1-phenylsulfonylindole-3-acetamide derivatives

Indole-3-acetic acid was esterified to give methyl ester (2), which was treated with substituted aromatic sulphonyl chloride in alkaline media to give 2-[1-(phenyl sufonyl-1H-indole-3-yl]methyl acetate (3). Further the compound 3 was converted to acid (4). Finally compound 4 was coupled with 6-substituted benzothiazole-2-amines by means of EDC to give acetamide derivatives (5a-i). The structures of the newly synthesized compounds have been established by analytical and spectral methods. These compounds have also been screened for analgesic activity.