1391850-52-4Relevant academic research and scientific papers
Diastereoselective synthesis of seven-membered-ring trans-alkenes from dienes and aldehydes by silylene transfer
Greene, Margaret A.,Prevost, Michel,Tolopilo, Joshua,Woerpel
, p. 12482 - 12484 (2012)
Silver-catalyzed silylene transfer to alkenes forms vinylsilacyclopropanes regioselectively. These allylic silanes undergo additions to aldehydes to form seven-membered-ring trans-alkenes with high diastereoselectivity. The high reactivity of the trans-alkenes is evidenced by their formal [1,3]-sigmatropic rearrangement reactions and the rapid additions of oxygen-hydrogen bonds across the carbon-carbon double bonds.
