1391908-86-3

Upstream product

• 1391908-83-0 methyl (R)-[1-(benzoyloxy)-2-(trityloxy)ethyl]-9H-pyrido[3,4-b]indole-3-carboxylate 
• 1391908-82-9 methyl (S)-1-[1-hydroxy-2-(trityloxy)ethyl]-9H-pyrido[3,4-b]indole-3-carboxylate 
• 66154-43-6 methyl (S)-1-(2,2-dimethyl-1,3-dioxolan-4-yl)-9H-pyrido[3,4-b]indole-3-carboxylate 
• 1391908-85-2 methyl (S)-1-[1-(benzoyloxy)ethyl]-9H-pyrido[3,4-b]indole-3-carboxylate 
• 1391908-79-4 methyl (R)-[1-(benzoyloxy)-2-iodoethyl]-9H-pyrido[3,4-b]indole-3-carboxylate 
• 1391908-84-1 methyl (R)-[1-(benzoyloxy)-2-(methylsulfonyloxy)ethyl]-9H-pyrido[3,4-b]indole-3-carboxylate 
• 1391908-80-7 methyl (R)-[1-(benzoyloxy)-2-hydroxyethyl]-9H-pyrido[3,4-b]indole-3-carboxylate 
• 1042149-39-2 methyl (S)-1-(1,2-dihydroxyethyl)-9H-pyrido[3,4-b]indole-3-carboxylate 
• 54731-09-8 N-tosyl-L-prolyl chloride 

Relevant academic research and scientific papers

Total syntheses of dichotomines A-D and the stereochemical revision of dichotomines B-D

New asymmetric total syntheses of (-)-dichotomines A-D (1-4) starting from L-tryptophan methyl ester and 2,3-O-isopropylidene-D-glyceraldehyde are described. The absolute configuration of the stereogenic center of (-)-dichotomine A (1) was reconfirmed as (S), on the basis of the X-ray crystallographic analysis of the conjugate (i.e., 17) of its methyl ester (i.e., 16) with (S)-N-tosylproline, whereas the absolute configurations of the stereogenic centers of (-)-dichotomines B-D (2-4) were revised as (R). Copyright