1391974-71-2

Basic information

• Product Name: C₂₀H₁₁ClF₂N₂O₂S
• CAS NO: 1391974-71-2
• Molecular Weight: 416.835
• Mol File: 1391974-71-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₀H₁₁ClF₂N₂O₂S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₀H₁₁ClF₂N₂O₂S(1391974-71-2)
• EPA Substance Registry System: C₂₀H₁₁ClF₂N₂O₂S(1391974-71-2)

Safety Data

• Hazardous Substances Data: 1391974-71-2(Hazardous Substances Data)

Upstream product

• 1042325-13-2 C₁₃H₇ClF₂N₂OS 
• 98-88-4 benzoyl chloride 
• 184839-29-0 2-(4-(2,6-difluorophenyl)thiazol-2-yl)acetonitrile 

Relevant articles and documents

Synthesis and antifungal activity of 2-thiazoleacrylonitrile derivatives

A coupling reaction of 2-[4-(2,6-difluorophenyl)thiazol-2-yl]acetonitrile and desired acid chlorides were occurred in the presence of triethylamine leading to 3-hydroxy-2-thiazolylacrylonitrile derivatives, then further reacted with acid chlorides to obtain twelve novel 3-esterified-2-thiazolylacrylonitrile derivatives (yields 70.8-87.3 %). The structures of the 2-thiazoleacrylonitrile derivatives were characterized by 1H NMR, mass spectra and elemental analysis. Antifungal activities against Fusarium oxysporium, Rhizoctonia solani, Botrytis cinereapers, Gibberella zeae, Colletotrichum gossypii were also evaluated by the mycelium growth rate method. The results indicated that these compounds possess certain antifungal activity.