1392224-24-6

Basic information

• Product Name: 5-chloro-3,4-ethylenedioxythiophene-2-carbaldehyde
• CAS NO: 1392224-24-6
• Molecular Weight: 204.634
• Mol File: 1392224-24-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-chloro-3,4-ethylenedioxythiophene-2-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-3,4-ethylenedioxythiophene-2-carbaldehyde(1392224-24-6)
• EPA Substance Registry System: 5-chloro-3,4-ethylenedioxythiophene-2-carbaldehyde(1392224-24-6)

Safety Data

• Hazardous Substances Data: 1392224-24-6(Hazardous Substances Data)

Upstream product

• 68-12-2 N,N-dimethyl-formamide 
• 302554-82-1 5-bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine 
• 174508-31-7 5,7-dibromo-2,3-dihydrothieno[3,4-b][1,4]dioxine 
• 126213-50-1 3,4-(ethylenedioxy)thiophene 

Relevant articles and documents

Chemistry of polyhalogenated nitrobutadienes, part 11: Ipso-formylation of 2-chlorothiophenes under Vilsmeier-Haack conditions

The regioselective ipso-formylation of electron-rich, 3,4-push-pull- substituted 2-chlorothiophenes under Vilsmeier-Haack conditions was performed in good yields. The synthetic scope of this new reaction was explored using various halothiophenes, chloroanilines, and 1-methyl-3-chloroindole. In comparison with their structural C-H analogs the chlorinated thiophenes, anilines, and the indole proved to be less reactive toward electrophilic attack by chloromethyleniminium salts.