139223-52-2

Basic information

• Product Name: N-{(R)-1-[2-((S)-Butane-1-sulfinyl)-phenyl]-ethyl}-2,2-dimethyl-propionamide
• CAS NO: 139223-52-2
• Molecular Weight: 309.473
• Mol File: 139223-52-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-{(R)-1-[2-((S)-Butane-1-sulfinyl)-phenyl]-ethyl}-2,2-dimethyl-propionamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-{(R)-1-[2-((S)-Butane-1-sulfinyl)-phenyl]-ethyl}-2,2-dimethyl-propionamide(139223-52-2)
• EPA Substance Registry System: N-{(R)-1-[2-((S)-Butane-1-sulfinyl)-phenyl]-ethyl}-2,2-dimethyl-propionamide(139223-52-2)

Safety Data

• Hazardous Substances Data: 139223-52-2(Hazardous Substances Data)

Upstream product

• 3282-30-2 pivaloyl chloride 
• 130973-54-5 (R)-(-)-o-(1-pivaloylaminoethyl)benzene sulfinic acid 
• 91797-84-1 (R)-(+)-N-(1-phenylethyl)-2,2-dimethylpropanamide 
• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 109-72-8 n-butyllithium 
• 139343-81-0 (S_(S)R)-(+)-3-methyl-2-pivaloyl-2,3-dihydroisothiazole 1-oxide 

Relevant articles and documents

Dependence of Ring Closure Stereoselectivity on the Nature of the Leaving Group: Application to the Synthesis of a New Class of Chiral Sulfoxide for the Control of Asymmetric Aldol Reactions

Enantiomerically pure cyclic sulfinamide (S(S)R)-(+)-1 , which has application to the control of asymmetric aldol reactions via a derived sulfoxide, has been prepared in diastereoisomerically pure form from the sulfinic acid (R)-(-)-5 using thionyl chloride-4-dimethylaminopyridine (DMAP); replacement of DMAP with pyridine or triethylamine gave both diastereoisomers of 1 in low diastereoisomeric excess.