1392297-49-2Relevant academic research and scientific papers
Palladium-catalyzed direct C-H arylation of enamides with simple arenes
Pankajakshan, Sreekumar,Xu, Yun-He,Cheng, Jun Kee,Low, Man Ting,Loh, Teck-Peng
, p. 5701 - 5705 (2012/07/13)
Z only: An atom-economical synthetic route towards arylated Z-enamides through double C-H functionalization is described. The Z/E selectivity of the palladium-catalyzed monoarylation is absolute (step A in scheme), and the molecular complexity of the products can be further endowed by a sequential second arylation, which requires the use of trifluoracetic acid (TFA; step B). Copyright
