1392414-70-8Relevant articles and documents
Facile preparation of indoles and 1,2-benzothiazine 1,1-dioxides: Nucleophilic addition of sulfonamides to bromoacetylenes and subsequent palladium-catalyzed cyclization
Yamagishi, Masahito,Nishigai, Ken,Ishii, Azusa,Hata, Takeshi,Urabe, Hirokazu
supporting information; experimental part, p. 6471 - 6474 (2012/07/27)
Bromine as a double agent: The bromine atom in 1-bromo-1-alkynes works as an electron-withdrawing group to effect the nucleophilic addition of sulfonamides. It again plays a pivotal role in the palladium-catalyzed cyclization of the resultant (Z)-2-(sulfonylamino)-1-bromoalkenes into nitrogen heterocycles (see scheme). Copyright