1392497-89-0

Basic information

• Product Name: 3-(2,4,5-trimethoxyphenyl)-(2E)-2-propen-1-ol
• Synonyms: 3-(2,4,5-trimethoxyphenyl)-(2E)-2-propen-1-ol
• CAS NO: 1392497-89-0
• Molecular Weight: 224.257
• Mol File: 1392497-89-0.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 3-(2,4,5-trimethoxyphenyl)-(2E)-2-propen-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2,4,5-trimethoxyphenyl)-(2E)-2-propen-1-ol(1392497-89-0)
• EPA Substance Registry System: 3-(2,4,5-trimethoxyphenyl)-(2E)-2-propen-1-ol(1392497-89-0)

Safety Data

• Hazardous Substances Data: 1392497-89-0(Hazardous Substances Data)

Upstream product

• 1269809-35-9 (E)-3-(2,4,5-trimethoxyphenyl)allyl acetate 
• 2883-98-9 α-asarone 
• 80749-75-3 (E)-3-(2,4,5-trimethoxy-phenyl)-acrylic acid methyl ester 
• 14469-89-7 trans-2,4,5-trimethoxycinnamic acid ethyl ester 
• 4460-86-0 asaraldehyde 
• 1402544-70-0 (Z)-3'-hydroxyasarone 

Downstream Products

• 99217-07-9 trans 2,4,5-trimethoxy cinnamaldehyde 

Relevant articles and documents

Metabolism of carcinogenic alpha-asarone by human cytochrome P450 enzymes

Major metabolites of alpha-asarone in liver microsomes are epoxide-derived side-chain diols. The intermediately formed epoxides are mutagenic and form DNA adducts and thus are likely responsible for the (hepato) carcinogenic effect of alpha-asarone observ

Synthesis methods of alpha-asarinol acetate and alpha-asarinol

The invention discloses synthesis methods of alpha-asarinol acetate and alpha-asarinol. The synthesis method of alpha-asarinol acetate comprises the following step that: in the presence of a palladium catalyst and a ligand, 1, 2, 4-trimethoxybenzene reacts with allyl acetate to generate the alpha-asarinol acetate, wherein the ligand is one or a combination of more than two of acetylglycine, acetylproline and nicotinoyl glycine. The synthesis method of the alpha-asarinol comprises the step of hydrolyzing alpha-asarinol acetate under an alkaline condition to obtain the alpha-asarinol. The methods have the advantages of simple and easily available raw materials, high atom economy and step economy, high yield and suitability for large-scale industrial production.

a-ASARY-LALDEHYDE ESTER, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF

The present invention relates to α-asary-laldehyde ester, a preparation method therefor, and an application thereof. The chemical structure of the related α-asary-laldehyde ester is represented by formula I. A related application is an application of the compound in preparation of drugs for calming, mind tranquillizing, senile dementia resisting, convulsion resisting, epilepsy resisting and depression resisting.