1269809-35-9Relevant academic research and scientific papers
Synthesis methods of alpha-asarinol acetate and alpha-asarinol
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Paragraph 0026; 0035-0061, (2021/08/14)
The invention discloses synthesis methods of alpha-asarinol acetate and alpha-asarinol. The synthesis method of alpha-asarinol acetate comprises the following step that: in the presence of a palladium catalyst and a ligand, 1, 2, 4-trimethoxybenzene reacts with allyl acetate to generate the alpha-asarinol acetate, wherein the ligand is one or a combination of more than two of acetylglycine, acetylproline and nicotinoyl glycine. The synthesis method of the alpha-asarinol comprises the step of hydrolyzing alpha-asarinol acetate under an alkaline condition to obtain the alpha-asarinol. The methods have the advantages of simple and easily available raw materials, high atom economy and step economy, high yield and suitability for large-scale industrial production.
Pd(ii)-catalyzed decarboxylative allylation and Heck-coupling of arene carboxylates with allylic halides and esters
Wang, Jiantao,Cui, Zili,Zhang, Yuexia,Li, Huajie,Wu, Long-Min,Liu, Zhongquan
supporting information; experimental part, p. 663 - 666 (2011/03/22)
This work demonstrates an alternative method to prepare allylated arenes and aryl-substituted allylic esters via catalytic decarboxylative C-C bond formation using aromatic carboxylic acids and allylic halides and esters.
