139255-97-3

Basic information

• Product Name: (4R)-2,2-dimethyl-4-phenyl-3-<(5S)-3-phenyl-2-isoxazoline-5-carbonyl>oxazolidine
• Synonyms: (4R)-2,2-dimethyl-4-phenyl-3-<(5S)-3-phenyl-2-isoxazoline-5-carbonyl>oxazolidine
• CAS NO: 139255-97-3
• Molecular Weight: 350.417
• Mol File: 139255-97-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (4R)-2,2-dimethyl-4-phenyl-3-<(5S)-3-phenyl-2-isoxazoline-5-carbonyl>oxazolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (4R)-2,2-dimethyl-4-phenyl-3-<(5S)-3-phenyl-2-isoxazoline-5-carbonyl>oxazolidine(139255-97-3)
• EPA Substance Registry System: (4R)-2,2-dimethyl-4-phenyl-3-<(5S)-3-phenyl-2-isoxazoline-5-carbonyl>oxazolidine(139255-97-3)

Safety Data

• Hazardous Substances Data: 139255-97-3(Hazardous Substances Data)

Upstream product

• 873-67-6 benzonitrile oxide 
• 139255-93-9 acrylic 2,2-dimethyl-5(R)-phenyl-1,3-oxazolidinide 
• 4872-58-6 3-phenyl-4,5-dihydroisoxazole-5-carboxylic acid 
• 698-16-8 benzohydroximoyl chloride 
• 139255-94-0 (4R)-2,2-dimethyl-4-phenyl-1,3-oxazolidine 
• 56613-80-0 D-2-phenylglycinol 

Downstream Products

• 139256-00-1 N-<(1R)-2-hydroxy-1-phenylethyl>-(5S)-3-phenyl-2-isoxazoline-5-carboxamide 

Relevant articles and documents

Highly lk-Selective Asymmetric Nitrile Oxide Cycloadditions to a C2-Symmetric 1,3-Diacryloyl-2,2-dimethylimidazolidine and 4-Chiral 3-Acryloyl-2,2-dialkyloxazolidines

1,3-Dipolar cycloadditions of benzonitrile oxide to the acrylamides derived from a C2-symmetric 2,2-dimethylimidazolidine and 4-chiral 2,2-dialkyloxazolidines show high lk-diasteroselectivities.Easy separation of the major lk-isomers from the minor ul-diastereomers is followed by reductive removal of the chiral auxiliaries to produce optically pure 2-isoxazoline-5-methanols.Absolute diastereoselectivities were recorded in the nitrile oxide cycloadditions of 3-acryloyl-2,2-dialkyl-4-(diphenylmethyl)oxazolidines at 0 deg C.