139285-03-3

Basic information

• Product Name: 1H-Imidazole, 4-(2-nitroethenyl)-1-(triphenylmethyl)-, (E)-
• CAS NO: 139285-03-3
• Molecular Formula: C24H19N3O2
• Molecular Weight: 381.434
• Mol File: 139285-03-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1H-Imidazole, 4-(2-nitroethenyl)-1-(triphenylmethyl)-, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Imidazole, 4-(2-nitroethenyl)-1-(triphenylmethyl)-, (E)-(139285-03-3)
• EPA Substance Registry System: 1H-Imidazole, 4-(2-nitroethenyl)-1-(triphenylmethyl)-, (E)-(139285-03-3)

Safety Data

• Hazardous Substances Data: 139285-03-3(Hazardous Substances Data)

Upstream product

• 33769-07-2 4-(hydroxymethyl)-1-(triphenylmethyl)imidazole 
• 76-83-5 trityl chloride 
• 75-52-5 nitromethane 
• 33016-47-6 (1-tritylimidazol-4-yl)carboxaldehyde 

Downstream Products

• 325688-90-2 (S)-4-Benzyl-3-[(2R,3R)-2-methyl-4-nitro-3-(1-trityl-1H-imidazol-4-yl)-butyryl]-oxazolidin-2-one 
• 325688-91-3 (3R,4R)-3-Methyl-4-(1-trityl-1H-imidazol-4-yl)-pyrrolidin-2-one 
• 325688-92-4 4-[(3R,4R)-4-methylpyrrolidin-3-yl]-1-trityl-1H-imidazole 
• 139285-09-9 4-(4,5-dimethyl-2-nitrocyclohex-4-en-1-yl)-1-(triphenylmethyl)-1H-imidazole 

Relevant articles and documents

Amine Catalysis with Substrates Bearing N-Heterocyclic Moieties Enabled by Control over the Enamine Pyramidalization Direction

Stereoselective organocatalytic C?C bond formations that tolerate N-heterocycles are valuable since these moieties are common motifs in numerous chiral bioactive compounds. Such transformations are, however, challenging since N-heterocyclic moieties can i

DIRECT ORGANOCATALYTIC ASYMMETRIC REACTIONS OF ENOLIZABLE α-AMINO ALDEHYDES OR KETONES TO FORM HIGHLY ENANTIOMERICALLY ENRICHED AMINE PRODUCTS

A method for asymmetrically forming a (diprotectedamino)-product having a chiral center and in which one enantiomer is in excess over the other is disclosed. The method comprises reacting an enolizable alpha- (diprotectedamino)-aldehyde or -ketone donor molecule with an excess of an unsaturated acceptor molecule that has one or no hydrogen atoms bonded to a carbon atom alpha to the carbon of the unsaturation. The donor and acceptor molecules are dissolved or dispersed in a liquid solvent and are in the presence of a chiral amine catalyst to form an addition product reaction medium. The reaction medium is maintained for a time sufficient to form an α-(diprotectedamino)-aldehyde or -ketone product having a chiral center formed at a carbon atom bonded to the α-(diprotectedamino) group and in which one enantiomer is in excess over the other.

Diels-Alder Reaction of (E)-4-(2-Nitroethenyl)-1H-imidazoles and Methyl (E)-3-(1-Imidazol-4-yl)propenoates

Diels-Alder reaction of methyl (E)-3-(1H-imidazol-4-yl)propenoates 2, 3a-c and (E)-4-(2-nitroethenyl)-1H-imidazoles 3d,e with 2,3-dimethyl-1,3-butadiene, cyclopentadiene, and cyclohexa-1,3-diene gave the corresponding cycloadducts 6-9.