139339-01-8

Basic information

• Product Name: 1,8-Naphthyridin-2(1H)-one, 4-amino-3-nitro-1-phenyl-
• CAS NO: 139339-01-8
• Molecular Formula: C14H10N4O3
• Molecular Weight: 282.258
• Mol File: 139339-01-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,8-Naphthyridin-2(1H)-one, 4-amino-3-nitro-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,8-Naphthyridin-2(1H)-one, 4-amino-3-nitro-1-phenyl-(139339-01-8)
• EPA Substance Registry System: 1,8-Naphthyridin-2(1H)-one, 4-amino-3-nitro-1-phenyl-(139339-01-8)

Safety Data

• Hazardous Substances Data: 139339-01-8(Hazardous Substances Data)

Usage

Chemical class

Naphthyridines

Core structure

Naphthyridinone

Amino group

At the 4-position

Nitro group

At the 3-position

Phenyl group

At the 1-position

Applications

Organic synthesis and medicinal chemistry

Pharmaceutical development

Used for developing various pharmaceuticals and agrochemicals

Biological activities

a. Anti-inflammatory
b. Anti-bacterial
c. Anti-cancer

Importance

Key molecule in drug discovery and development

Therapeutic applications

Studied for potential use in treating various diseases and disorders

Upstream product

• 139338-98-0 4-hydroxy-3-nitro-1-phenyl-1,8-naphthyridin-2(1H)-one 
• 138305-19-8 1-phenyl-2H-pyrido<2,3-d><1,3>oxazine-2,4(1H)-dione 
• 139338-99-1 4-chloro-3-nitro-1-phenyl-1,8-naphthyridin-2(1H)-one 

Downstream Products

• 160623-93-8 3,4-diamino-1-phenyl-1,8-naphthyridin-2(1H)-one 
• 139339-02-9 5-phenyl-1H-imidazo<4,5-c><1,8>naphthyridin-4(5H)-one 
• 139360-51-3 3-methyl-5-phenyl-3H-imidazo<4,5-c><1,8>naphthyridin-4(5H)-one 
• 139339-09-6 3-Ethyl-5-phenyl-3H-imidazo[4,5-c][1,8]naphthyridin-4(5H)-one 
• 139339-10-9 3-Isopropyl-5-phenyl-3,5-dihydro-1,3,5,6-tetraaza-cyclopenta[a]naphthalen-4-one 
• 139339-11-0 3-benzyl-5-phenyl-3H-imidazo[4,5-c][1,8]naphthyridin-4(5H)-one 
• 139482-62-5 3-benzyl-2,5-diphenyl-3H-imidazo<4,5-c><1,8>naphthyridin-4(5H)-one 
• 139482-61-4 3-benzyl-2-methyl-5-phenyl-3H-imidazo<4,5-c><1,8>naphthyridin-4(5H)-one 
• 139482-20-5 2,5-diphenyl-3H-imidazo<4,5-c><1,8>naphthyridin-4(5H)-one 
• 139482-19-2 2-methyl-5-phenyl-3H-imidazo<4,5-c><1,8>naphthyridin-4(5H)-one 

Relevant articles and documents

Imidazonaphthyridine derivatives

The present invention relates to novel imidazonaphthyridine derivatives represented by the following formulae: STR1 wherein R represents hydrogen, lower alkyl or --CH2 R1 (where R1 represents phenyl or pyridyl) and pharmac

A Facile and Novel Synthesis of 5-Phenylimidazonaphthyridin-4(5H)-ones

A convenient and regioselective synthesis of a new heterocycle, 5-phenyl-1H or 3H-imidazonaphthyridin-4(5H)-one 1-a or 1-b, is described.Methyl 2-anilinonicotinate 15 was transformed into the valuable intermediate, N-phenyl-3-azaisatoic anhydr