139338-98-0

Upstream product

• 626-35-7 nitroacetic acid ethyl ester 
• 138305-19-8 1-phenyl-2H-pyrido<2,3-d><1,3>oxazine-2,4(1H)-dione 
• 89109-17-1 4-hydroxy-1-phenyl-1,8-naphthyridin-2(1H)-one 
• 154194-36-2 4-hydroxy-3-nitroso-1-phenyl-1,8-naphthyridin-2(1H)-one 

Downstream Products

• 139338-99-1 4-chloro-3-nitro-1-phenyl-1,8-naphthyridin-2(1H)-one 
• 139339-05-2 4-Benzylamino-3-nitro-1-phenyl-1,8-naphthyridin-2(1H)-one 
• 139339-11-0 3-benzyl-5-phenyl-3H-imidazo[4,5-c][1,8]naphthyridin-4(5H)-one 
• 139339-08-5 1-Benzyl-5-phenyl-1H-imidazo[4,5-c][1,8]naphthyridin-4(5H)-one 
• 139339-04-1 4-Isopropylamino-3-nitro-1-phenyl-1,8-naphthyridin-2(1H)-one 
• 139339-10-9 3-Isopropyl-5-phenyl-3,5-dihydro-1,3,5,6-tetraaza-cyclopenta[a]naphthalen-4-one 
• 139339-07-4 1-Isopropyl-5-phenyl-1H-imidazo[4,5-c][1,8]naphthyridin-4(5H)-one 
• 139339-03-0 4-Ethylamino-3-nitro-1-phenyl-1,8-naphthyridin-2(1H)-one 
• 139339-00-7 4-methylamino-3-nitro-1-phenyl-1,8-naphthyridin-2(1H)-one 
• 139339-06-3 1-Ethyl-5-phenyl-1H-imidazo[4,5-c][1,8]naphthyridin-4(5H)-one 
• 139339-01-8 4-amino-3-nitro-1-phenyl-1,8-naphthyridin-2(1H)-one 
• 139339-09-6 3-Ethyl-5-phenyl-3H-imidazo[4,5-c][1,8]naphthyridin-4(5H)-one 
• 139360-51-3 3-methyl-5-phenyl-3H-imidazo<4,5-c><1,8>naphthyridin-4(5H)-one 
• 139338-97-9 1-methyl-5-phenyl-1H-imidazo<4,5-c><1,8>naphthyridin-4(5H)-one 

Relevant academic research and scientific papers

Imidazonaphthyridine derivatives

The present invention relates to novel imidazonaphthyridine derivatives represented by the following formulae: STR1 wherein R represents hydrogen, lower alkyl or --CH2 R1 (where R1 represents phenyl or pyridyl) and pharmac

A facile synthesis of 5-phenylimidazo-[4,5-c] [1,8]naphthyridin-4(5H)-one

1-Phenyl-3-nitroso-4-amino-1,8-naphthyridin-2(1H)-one (9) was prepared on a large scale and was converted to 5-phenyl-imidazo[4,5-c] [1,8]naphthyridin-4(5H)-one (KF17625, 1) which exhibitis potent antiasthmatic activity.

A Facile and Novel Synthesis of 5-Phenylimidazonaphthyridin-4(5H)-ones

A convenient and regioselective synthesis of a new heterocycle, 5-phenyl-1H or 3H-imidazonaphthyridin-4(5H)-one 1-a or 1-b, is described.Methyl 2-anilinonicotinate 15 was transformed into the valuable intermediate, N-phenyl-3-azaisatoic anhydr

4-Hydroxy-3-nitro-pyrido[2,3-B]pyridine-2(1H)-ones

Anti-allergic 4-hydroxy-3-nitro-pyrido[2,3-b]pyridines-2(1H)-ones are prepared by reacting a 3,4-dihydro-1,3-dioxo-1H-pyrido[2,3-d][1,3]oxazine (a 3-azaisatoic anhydride) with the carbanion resulting from the reaction of nitro acetic acid alkyl esters with a proton abstracting agent.