1393480-80-2Relevant academic research and scientific papers
Pd-catalyzed C-H olefination of (hetero)arenes by using saturated ketones as an olefin source
Shang, Yaping,Jie, Xiaoming,Zhou, Jun,Hu, Peng,Huang, Shijun,Su, Weiping
supporting information, p. 1299 - 1303 (2013/03/13)
Tolerant: By using Pd(OAc)2/PCy3 as a catalyst, both electron-rich aromatic heterocycles and electron-deficient fluorobenzenes undergo the dehydrogenative cross-coupling with (hetero)aryl ethyl ketones in good yields. A broad range of functional groups is tolerated, thus providing a general method for the facile syntheses of chalcones or heterocyclic chalcone analogues. Furthermore, dialkyl ketones can also participate in this transformation. Copyright
