139356-40-4

Upstream product

• 387834-48-2 [(R)-6-{(E,3R,3aR)-7-(bromomethylene)octahydro-3a-methyl-1H-inden-3-yl}-2-methylheptan-2-yloxy]trimethylsilane 
• 387834-44-8 (1R,5R)-(Z)-3-bromomethylene-5-(tert-butyldimethyl-silanyloxy)cyclohexanol 
• 387834-43-7 (1R,4R,6S)-(E)-2-bromomethylene-4-(tert-butyldimethylsilyloxy)-7-oxa-bicyclo[4.1.0]heptane 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 387834-49-3 (1R,3aS,7aR)-(E)-2-{1-[(R)-1,5-dimethyl-5-(trimethylsilanyloxy)hexyl]-7a-methyloctahydroinden-4-ylidenemethyl}-4,4,5,5-tetramethyl[1,3,2]dioxaborolane 
• 512790-89-5 (1R,3R)-1,3-Bis-(tert-butyl-dimethyl-silanyloxy)-5-((E)-(R)-7,11-dimethyl-11-triethylsilanyloxy-dodec-2-enylidene)-cyclohexane 
• 387834-42-6 (3R,5R)-2-[3,5-bis-(tert-butyldimethylsilanyloxy)cyclohexylidenemethyl]-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane 
• 139356-33-5 (3S,5S)-3,5-bis[(tert-butyl)dimethylsilyloxy]-1-hydroxycyclohexane-1-carboxylic acid methyl ester 
• 139356-38-0 ((1R,3R)-5-(2-chloroethylidene)cyclohexane-1,3-diyl)bis(oxy)bis(tert-butyldimethylsilane) 
• 139356-37-9 [(3R,5R)-3,5-bis-(tert-butyldimethylsilanyloxy)cyclohexylidene]-ethanol 
• 139356-35-7 3,5-di-(tert-butyl-dimethylsilyloxy)-(3S,5S)-cyclohexan-1-one 
• 139356-34-6 (3S,5S)-3,5-bis[tert-butyl(dimethyl)silyloxy]-1-(hydroxylmethyl)cyclohexanol 
• 135711-62-5 methyl quinicate 
• 191916-39-9 methyl (-)-quinate 

Downstream Products

• 130447-37-9 1α,25-dihydroxy-19-nor-vitamin D₃ 

Relevant academic research and scientific papers

Process for the synthesis of vitamin d compounds and intermediates for the synthesis of the compounds

An object of the present invention is to provide a process for synthesizing a vitamin D compound by simple procedures at lower costs. The present invention provides a process for preparing a vitamin D compound and an intermediate thereof, comprising the s

Novel synthetic approach to 19-nor-1α,25-dihydroxyvitamin D3 and its derivatives by Suzuki-Miyaura coupling in solution and on solid support

equation presented 19-nor-1α,25-Dihydroxyvitamin D3 was synthesized by the Suzuki-Miyaura coupling of the A-ring intermediate 3, which was efficiently prepared from readily available 5-(tert-butyldimethylsilyl)oxycyclohex-2-enone (5), with the

Novel synthesis of 19-nor-vitamin D compounds

1α,25-Dihydroxy-19-nor-vitamin D3 was prepared efficiently in a convergent synthesis starting with (-)-quinic acid and a ketone of the Windaus-Grundmann type.