139356-38-0 Usage
Uses
Used in Pharmaceutical Industry:
((1R,3R)-5-(2-chloroethylidene)cyclohexane-1,3-diyl)bis(oxy)bis(tert-butyldimethylsilane) is used as a pharmaceutical intermediate for the synthesis of various drugs and active pharmaceutical ingredients. Its unique structure and functional groups enable it to serve as a key building block in the development of new medications.
Used in Chemical Synthesis:
In the field of chemical synthesis, ((1R,3R)-5-(2-chloroethylidene)cyclohexane-1,3-diyl)bis(oxy)bis(tert-butyldimethylsilane) is used as a versatile reagent and precursor in the preparation of a wide range of organic compounds. Its chloroethylidene and tert-butyldimethylsilane groups can be utilized in various chemical reactions, making it a valuable component in the synthesis of complex organic molecules.
Used in Material Science:
((1R,3R)-5-(2-chloroethylidene)cyclohexane-1,3-diyl)bis(oxy)bis(tert-butyldimethylsilane) is employed in material science as a component in the development of advanced materials with specific properties. Its unique structure and functional groups can contribute to the creation of materials with tailored characteristics, such as improved stability, reactivity, or selectivity, depending on the application.
Used in Research and Development:
In research and development, ((1R,3R)-5-(2-chloroethylidene)cyclohexane-1,3-diyl)bis(oxy)bis(tert-butyldimethylsilane) serves as a valuable compound for studying the properties and behavior of complex organic molecules. Its unique structure and functional groups make it an interesting subject for investigations into chemical reactions, mechanisms, and the development of new synthetic methods.
Check Digit Verification of cas no
The CAS Registry Mumber 139356-38-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,9,3,5 and 6 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 139356-38:
(8*1)+(7*3)+(6*9)+(5*3)+(4*5)+(3*6)+(2*3)+(1*8)=150
150 % 10 = 0
So 139356-38-0 is a valid CAS Registry Number.
139356-38-0Relevant academic research and scientific papers
Preparation method of paricalcitol intermediate
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, (2018/01/11)
The invention discloses a preparation method of a paricalcitol intermediate, which includes the following steps: (1) shikimic acid is esterified; (2) hydroxyl groups at sites 3 and 5 are selectively protected; (3) hydroxyl group at site 4 is protected by
A new metabolite of Paricalcitol: stereoselective synthesis of (22Z)-isomer of 1α,25-dihydroxy-19-norvitamin D2
Samala, Ramakrishna,Sharma, Somesh,Basu, Manas K.,Mukkanti,Porstmann, Frank
, p. 1309 - 1312 (2018/03/26)
Stereoselective synthesis of (22Z)-isomer of Paricalcitol, an analog of 1,25-dihydroxyergocalciferol, an active form of vitamin D2 (Ergocalciferol) has been described. The two key critical synthetic steps involved are Julia–Lythgoe's Wittig–Hor
1-DEOXY ANALOGS OF VITAMIN D-RELATED COMPOUNDS
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, (2011/08/04)
This present disclosure is directed to novel prodrugs of activated vitamin D3 compounds. The prodrugs can be designed to have one or more beneficial properties, such as selective inhibition of the enzyme CYP24, low calcemic activity, and anti-proliferativ
Asymmetric synthesis of a key ring a synthon for 1α-hydroxy-19-nor vitamin D
Courtney, Lawrence F.,Lange, Meinolf,Uskokovic, Milan R.,Wovkulich, Peter M.
, p. 3363 - 3366 (2007/10/03)
A diasteroselective carbonyl ene reaction on a substrate obtained from a regioselective propiolate ene reaction is described for the synthesis of 19- nor A-ring synthon 3.
Novel synthesis of 19-nor-vitamin D compounds
Perlman, Kato L.,Swenson, Rolf E.,Paaren, Herbert E.,Schnoes, Heinrich K.,DeLuca, Hector F.
, p. 7663 - 7666 (2007/10/02)
1α,25-Dihydroxy-19-nor-vitamin D3 was prepared efficiently in a convergent synthesis starting with (-)-quinic acid and a ketone of the Windaus-Grundmann type.
