1393669-61-8Relevant articles and documents
Exploration of the SAR of anti-invasive chalcones: Synthesis and biological evaluation of conformationally restricted analogues
Roman, Bart I.,Ryck, Tine De,Dierickx, Laura,Vanhoecke, Barbara W.A.,Katritzky, Alan R.,Bracke, Marc,Stevens, Christian V.
, p. 4812 - 4819 (2012)
In order to get a clearer view on the active geometry of anti-invasive chalcones, we have prepared a number of isoxazoles and related substances as conformationally restrained mimics of 1,3-diarylpropenones, and also of (Z)-stilbenes. In vitro anti-invasi