1393673-69-2Relevant academic research and scientific papers
A new synthetic strategy for catechin-class polyphenols: Concise synthesis of (-)-epicatechin and its 3-O-gallate
Stadlbauer, Sven,Ohmori, Ken,Hattori, Fumihiko,Suzuki, Keisuke
supporting information, p. 8425 - 8427 (2012/10/29)
Concise synthesis of (-)-epicatechin and its 3-O-gallate is described, illustrating efficacy of the new strategy for catechin-class polyphenols based on assembly of lithiated fluorobenzene and epoxy alcohol followed by a pyran cyclization. 1,3,5-Trifluorobenzene serves as the A-ring equivalent for functionalization and the pyran annulation.
