88191-48-4

Usage

Definition

ChEBI: The monohydrate of (+)-catechin.

InChI:InChI=1/C15H14O6.H2O/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7;/h1-5,13,15-20H,6H2;1H2/t13-,15+;/m0./s1

Upstream product

• 87292-49-7 5,7,3',4'-tetra-O-benzylepicatechin 
• 1393673-71-6 C₄₇H₄₇FO₈ 
• 1393673-70-5 C₅₃H₆₁FO₈Si 
• 1393673-69-2 C₄₉H₅₃FO₆Si 
• 372-38-3 1,3,5-trifluorobenzene 

Downstream Products

• 246181-58-8 Bis-[(2R,3S)-2-(3,4-dihydroxy-phenyl)-3,5,7-trihydroxy-chroman-8-yl]-acetic acid 

Relevant academic research and scientific papers

A new synthetic strategy for catechin-class polyphenols: Concise synthesis of (-)-epicatechin and its 3-O-gallate

Concise synthesis of (-)-epicatechin and its 3-O-gallate is described, illustrating efficacy of the new strategy for catechin-class polyphenols based on assembly of lithiated fluorobenzene and epoxy alcohol followed by a pyran cyclization. 1,3,5-Trifluorobenzene serves as the A-ring equivalent for functionalization and the pyran annulation.

Crystal modifications of (+)-catechin and pharmaceutical preparations containing them

Novel crystal modifications of (+)-catechin monohydrate and of (+)-catechin anhydrate more suitable for pharmaceutical preparations for reasons of higher stability against moisture and/or light and distinguished from hitherto known modifications by unique X-ray diffraction spectra are produced by specific recrystallization and/or crystal rearrangement processes and pharmaceutical preparations comprising the novel crystal forms.