1393739-69-9Relevant articles and documents
Proline-cyclodextrin conjugates: Synthesis and evaluation as catalysts for aldol reaction in water
Doyagüez, Elisa G.,Fernández-Mayoralas, Alfonso
, p. 7345 - 7354 (2012)
The synthesis of six conjugates of l-proline and β-cyclodextrin and their evaluation as catalysts of aldol reaction in water are described. The results indicated that the nature of the linker between proline and β-cyclodextrin is important for catalytic activity; the one with the most flexible linker gave the best results. Inhibition experiments showed that the cavity of β-cyclodextrin plays a role in the catalysis. Permethylation of the cyclodextrin hydroxyl groups led to higher conversion rates.