329191-57-3

Basic information

• Product Name: (2S,4S)-N^α-Cbz-4-aminoproline benzyl ester
• Synonyms: (2S,4S)-N^α-Cbz-4-aminoproline benzyl ester
• CAS NO: 329191-57-3
• Molecular Weight: 354.406
• Mol File: 329191-57-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2S,4S)-N^α-Cbz-4-aminoproline benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4S)-N^α-Cbz-4-aminoproline benzyl ester(329191-57-3)
• EPA Substance Registry System: (2S,4S)-N^α-Cbz-4-aminoproline benzyl ester(329191-57-3)

Safety Data

• Hazardous Substances Data: 329191-57-3(Hazardous Substances Data)

Usage

General Description

(2S,4S)-Nα-Cbz-4-aminoproline benzyl ester is a chemical compound that is used in the synthesis of various peptides and proteins. It is a derivative of proline, an amino acid, and is commonly utilized as a building block in peptide synthesis. The compound is characterized by its N-terminus being protected with a carbobenzyloxy group (Cbz) and an ester bond with a benzyl group. This specific configuration allows for the controlled addition of the compound into peptide chains during synthesis. The chemical compound has applications in the pharmaceutical industry for the production of peptide-based drugs, as well as in research for the synthesis of custom peptides and proteins for various purposes.

Upstream product

• 81464-46-2 (2S,4S)-4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-pyrrolidine-1,2-dicarboxylic acid dibenzyl ester 
• 100-51-6 benzyl alcohol 
• 13504-85-3 (2S,4R)-1-(benzyloxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid 
• 159551-87-8 (2S,4R)-N^α-Cbz-4-[(p-toluenesulfonyl)oxy]proline benzyl ester 
• 13500-53-3 N-benzyloxycarbonyl-(2S,4R)-4-hydroxyproline benzyl ester 
• 329191-55-1 (2S,4S)-N^α-Cbz-4-azidoproline benzyl ester 

Downstream Products

• 1279034-78-4 (2S,4S)-4-tert-Butoxycarbonylamino-pyrrolidine-2-carboxylic acid 
• 221352-74-5 (2S,4S)-1-(((9H-fluoren-9-yl)methoxy)carbonyl)-4-(tert-butoxycarbonylamino)pyrrolidine2-carboxylic acid 
• 1146289-56-6 dibenzyl (2S,4S)-4-(4-methylphenylsulfonamido)pyrrolidine-1,2-dicarboxylate 
• 1000312-50-4 (2S,4S)-4-acetamido-1,2-dibenzyloxycarbonylpyrrolidine 
• 1393739-69-9 6(I)-[N'-(2S,4S)-1,2-dibenzyloxycarbonylpyrrolidin-4-yl]aminocarbonylethylcarbonylamino-6(I)-deoxy-β-cyclodextrin 
• 1352655-90-3 C₂₆H₂₉N₄O₅⁽¹⁺⁾*Cl^(1-) 
• 1352655-92-5 C₂F₆NO₄S₂^(1-)*C₂₆H₂₉N₄O₅⁽¹⁺⁾ 
• 1352655-89-0 N-benzyloxycarbonyl-(2S,4S)-4-(2-chloroacetamido)-proline benzyl ester 
• 853063-23-7 (2S,4S)-N^α-Cbz-4-N-Boc-aminoproline benzyl ester 
• 329191-59-5 (2S,4S)-N^α-Cbz-4-N,N'-di-Boc-guanidinoproline benzyl ester 

Relevant articles and documents

Asymmetric aldol reaction using immobilized proline on mesoporous support

The aldol reaction of hydroxyacetone with different aldehydes using immobilized proline on a mesoporous support, assisted by heat and microwaves, has been explored. It was found that heterogenized L-proline on MCM-41 catalyzed aldol reactions in both hydr