139374-05-3Relevant academic research and scientific papers
Dehydrooligopeptides. XVII. Practical syntheses of all of the diastereomers of N,N-protected 2,3-diaminobutanoic acids from L- and D-threonine derivatives
Nakamura,Hirai,Tamotsu,Yonezawa,Shin
, p. 1369 - 1377 (2007/10/02)
Syntheses of all of the dioctereomers of 2,3-diaminobutanoic acids, found in some pedtide antibiotics and toxins, were accomplished. The four isomers were derived mainly through two pathways including S(N)2 inversions of the β-substituent of L- or D-threonine derivatives. The various protecting groups and effective nucleophiles for the S(N)2 inversion were examined.
Facile Syntheses of (S,S)-2,3-Diaminobutyric Acid and Acid Containg N-Terminal Tripeptide of Antrimycins
Nakamura, Yutaka,Shin, Chung-gi
, p. 49 - 52 (2007/10/02)
The stereoselective synthesis of (S,S)-2,3-diaminobutyric acid (Dab), which is one of the four uncommon α-amino acid residues of antrimycins (1a) and cirratiomycins (1b), was accomplished.Furthermore, N-terminal tripeptide segment of 1 containing Dab resi
