139374-07-5

Upstream product

• 82353-55-7 benzyl (S)-1-oxopropan-2-ylcarbamate 
• 2592-18-9 Boc-Thr-OH 
• 15260-10-3 N-Boc-O-benzyl-L-threonine 
• 99216-67-8 2-<<(tert-butoxy)carbonyl>amino>butane-1,3-diol 
• 156173-87-4 (R)-4<(S)-1-(benzyloxycarbonylamino)ethyl>-3-t-butoxycarbonyl-2,2-dimethyl-1,3-oxazolidine 
• 156173-84-1 (R)-3-t-butoxycarbonyl-2,2-dimethyl-4<(R)-1-(methylsulfonyloxy)ethyl>-1,3-oxazolidine 
• 156173-86-3 (R)-4<(S)-1-azidoethyl>-3-t-butoxycarbonyl-2,2-dimethyl-1,3-oxazolidine 
• 156173-88-5 (2R,3S)-3-azido-2-(t-butoxycarbonyl)amino-1-butanol 
• 156173-83-0 (4R)-4-[(R)-1-hydroxyethyl]-2,2-dimethyl-N-(tert-butoxycarbonyl)-1,3-oxazolidine 
• 386749-97-9 3(S)-amino-2(R)-(tert-butyloxycarbonylamino)-O-tert-butyldimethylsilylbutanol 
• 99216-72-5 Boc-L-Thr(Ms)-OMe 
• 99216-73-6 N-<(1R,2R)-1-(Hydroxymethyl)-2-(methanesulfonyloxy)ethyl>-1-(1,1-dimethylethoxy)methanamide 
• 139374-05-3 (2R,3S)-3-(benzyloxycarbonyl)amino-2-(t-butoxycarbonyl)amino-1-(t-butyldimethyl)siloxybutane 
• 139374-04-2 (2R,3S)-3-azido-2-(t-butoxycarbonyl)amino-1-(t-butyldimethyl)siloxybutane 

Downstream Products

• 139374-11-1 (2S,3S)-3-Benzyloxycarbonylamino-2-tert-butoxycarbonylamino-butyric acid 2,2,2-trichloro-ethyl ester 
• 156174-01-5 (S)-4-benzyl-3-<(S)-2-<(2S,3S)-3-(benzyloxycarbonylamino)-2-(t-butoxycarbonylamino)butanoyl>-2,3,4,5-tetrahydro-3-pyridazinylcarbonyl>-2-oxazolidinone 
• 139374-13-3 Boc-HMSer(MOM)2-Ala-Dab(Cbz)-OTce 
• 139374-14-4 Boc-HMSer(MOM)2-Ala-Dab(Cbz)-OH 
• 139374-12-2 Boc-Ala-Dab(Cbz)-OTce 

Relevant academic research and scientific papers

Stereocontrolled synthesis of anti-α-hydroxy-β-amino and anti-α,β-diamino acid derivatives by epoxidation of 1-arylthio-1-nitroalkenes

Epoxidation of 1-tolylthio-1-nitroalkenes containing an allylic Boc-protected amino group yields cis-oxazolidinones 13, formed by intramolecular trapping of the presumed intermediate epoxides by the carbamate group. Epoxidation of the analogous Z- or Fmoc-protected derivatives yields the corresponding syn-epoxides which, although they cannot be isolated, can be trapped with aqueous ammonia, or more efficiently benzylamine, to give stereoisomerically pure anti-α,β-diamino acid derivatives.

Stereoselective synthesis of differentially protected anti-α,β-diamino acid derivatives using arylthionitrooxiranes

Epoxidation of 1-tolylthio-1-nitroalkenes containing an allylic Z- or Fmoc-protected amino group yields the corresponding syn-epoxides which, although they cannot be isolated, can be trapped with aqueous ammonia to give stereoisomerically pure anti-α,β-diamino acid derivatives.

Dehydrooligopeptides. XVII. Practical syntheses of all of the diastereomers of N,N-protected 2,3-diaminobutanoic acids from L- and D-threonine derivatives

Syntheses of all of the dioctereomers of 2,3-diaminobutanoic acids, found in some pedtide antibiotics and toxins, were accomplished. The four isomers were derived mainly through two pathways including S(N)2 inversions of the β-substituent of L- or D-threonine derivatives. The various protecting groups and effective nucleophiles for the S(N)2 inversion were examined.

Facile Syntheses of (S,S)-2,3-Diaminobutyric Acid and Acid Containg N-Terminal Tripeptide of Antrimycins

The stereoselective synthesis of (S,S)-2,3-diaminobutyric acid (Dab), which is one of the four uncommon α-amino acid residues of antrimycins (1a) and cirratiomycins (1b), was accomplished.Furthermore, N-terminal tripeptide segment of 1 containing Dab resi