1393807-47-0Relevant articles and documents
Ailanthoidol derivatives and their anti-inflammatory effects
Lee, Na Li,Lee, Jae Jun,Kim, Jin-Kyung,Jun, Jong-Gab
experimental part, p. 1907 - 1912 (2012/08/08)
Ailanthoidol showed a strong anti-inflammatory effect in a previous result. Ailanthoidol derivatives were prepared for the anti-inflammatory test using Sonogashira coupling, iodine induced cyclization and Wittig reaction. Anti-inflammatory effects of the prepared ailanthoidol derivatives were examined in lipopolysac-charide (LPS)-stimulated RAW 264-7 macrophages. The results showed that some ailanthoidol derivatives inhibited significantly the production of inflammatory mediator nitric oxide.