220882-37-1Relevant articles and documents
Triazole compounds as well as preparation method and application thereof
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, (2020/07/29)
The invention belongs to the technical field of medicinal chemistry, and particularly relates to triazole compounds and a preparation method and application thereof. The triazole compounds have excellent LPAR1 antagonistic activity and selectivity, are lo
Tandem Claisen Rearrangement/6-endo Cyclization Approach to Allylated and Prenylated Chromones
Schmidt, Bernd,Riemer, Martin,Schilde, Uwe
supporting information, p. 7602 - 7611 (2016/01/25)
Allyl, dimethylallyl and prenyl ethers derived from o-acylphenols reacted upon microwave irradiation to form C-allylated or -prenylated chromone derivatives, depending on the substitution pattern of the arene and the allyl substituent. The reaction proceeds through a tandem Claisen rearrangement and 6-endo-trig or 6-endo-dig cyclization sequence. For prenyl ethers, the tandem sequence can be extended by a Cope rearrangement to furnish 6-prenylchromones. The method is potentially useful for the synthesis of natural products and drugs.
Synthesis of naturally occurring norlignan (±)-nyasol
Kwon, Jinsun,Kondaji, Gajulapati,Song, Sumi,Kim, Chorong,Lee, Kyeong,Kim, Won-Ki,Choi, Yongseok
, p. 1247 - 1249 (2013/07/28)
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