1393843-21-4

Basic information

• Product Name: 2-(2-chloro-6-fluorophenyl)-N-[2-chloro-6-(trifluoromethyl)phenyl]-4,4-dimethyl-1,4-dihydrochromeno[3,4-d]imidazole-7-carboxamide
• Synonyms: 2-(2-chloro-6-fluorophenyl)-N-[2-chloro-6-(trifluoromethyl)phenyl]-4,4-dimethyl-1,4-dihydrochromeno[3,4-d]imidazole-7-carboxamide
• CAS NO: 1393843-21-4
• Molecular Weight: 550.339
• Mol File: 1393843-21-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(2-chloro-6-fluorophenyl)-N-[2-chloro-6-(trifluoromethyl)phenyl]-4,4-dimethyl-1,4-dihydrochromeno[3,4-d]imidazole-7-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-chloro-6-fluorophenyl)-N-[2-chloro-6-(trifluoromethyl)phenyl]-4,4-dimethyl-1,4-dihydrochromeno[3,4-d]imidazole-7-carboxamide(1393843-21-4)
• EPA Substance Registry System: 2-(2-chloro-6-fluorophenyl)-N-[2-chloro-6-(trifluoromethyl)phenyl]-4,4-dimethyl-1,4-dihydrochromeno[3,4-d]imidazole-7-carboxamide(1393843-21-4)

Safety Data

• Hazardous Substances Data: 1393843-21-4(Hazardous Substances Data)

Upstream product

• 1393843-94-1 4-hydroxyphenyl-2-(2-chloro-6-fluorophenyl)-4,4-dimethyl-1,4-dihydrochromeno[3,4-d]imidazole-7-carboxylate 
• 433-94-3 2-chloro-6-(trifluoromethyl)benzenamine 

Relevant articles and documents

TRICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS

The present invention relates to tricyclic compounds of formula (I) or pharmaceutically acceptable salt thereof as mPGES-1 inhibitors. These compounds are inhibitors of the microsomal prostaglandin E synthase-1 (mPGES-1) enzyme and are therefore useful in the treatment of pain and/or inflammation from a variety of diseases or conditions, such as asthama, osteoarthritis, rheumatoid arthritis, acute or chronic pain and neurodegenerative diseases. (I)