1393901-34-2

Basic information

• Product Name: tert-butyl 4-(4-((4-(3-carbamoyl-4-methylphenethyl)-5-(trifluoromethyl)pyrimidin-2-yl)amino)phenyl)piperazine-1-carboxylate
• Synonyms: tert-butyl 4-(4-((4-(3-carbamoyl-4-methylphenethyl)-5-(trifluoromethyl)pyrimidin-2-yl)amino)phenyl)piperazine-1-carboxylate
• CAS NO: 1393901-34-2
• Molecular Weight: 584.642
• Mol File: 1393901-34-2.mol

Chemical Properties

• CAS DataBase Reference: tert-butyl 4-(4-((4-(3-carbamoyl-4-methylphenethyl)-5-(trifluoromethyl)pyrimidin-2-yl)amino)phenyl)piperazine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 4-(4-((4-(3-carbamoyl-4-methylphenethyl)-5-(trifluoromethyl)pyrimidin-2-yl)amino)phenyl)piperazine-1-carboxylate(1393901-34-2)
• EPA Substance Registry System: tert-butyl 4-(4-((4-(3-carbamoyl-4-methylphenethyl)-5-(trifluoromethyl)pyrimidin-2-yl)amino)phenyl)piperazine-1-carboxylate(1393901-34-2)

Safety Data

• Hazardous Substances Data: 1393901-34-2(Hazardous Substances Data)

Upstream product

• 1393900-79-2 tert-butyl 4-(4-((4-chloro-5-(trifluoromethyl)pyrimidin-2-yl)amino)phenyl)piperazine-1-carboxylate 
• 79669-49-1 5-bromo-2-methylbenzoic acid 
• 260252-87-7 4-(4'-nitrophenyl)piperazine hydrochloride 
• 24424-99-5 di-tert-butyl dicarbonate 
• 170911-92-9 4-(4-aminophenyl)-1-t-butyloxycarbonylpiperazine 
• 182618-86-6 tert-butyl 4-(4-nitrophenyl)piperazine-1-carboxylate 
• 1393901-33-1 tert-butyl 4-(4-((4-((3-carbamoyl-4-methylphenyl)ethynyl)-5-(trifluoromethyl)pyrimidin-2-yl)amino)phenyl)piperazine-1-carboxylate 
• 1393901-32-0 5-ethynyl-2-methylbenzamide 
• 1393901-31-9 2-methyl-5-((trimethylsilyl)ethynyl)benzamide 
• 854633-21-9 5-bromo-2-methylbenzamide 

Downstream Products

• 1393900-57-6 2-methyl-5-(2-(2-((4-(piperazin-1-yl)phenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)ethyl)benzamide 

Relevant articles and documents

FAK AND FLT3 INHIBITORS

The use of a compound of the formula (I): (Formula (I)) in the preparation of a medicament for treating Acute Myeloid Leukemia or a disease ameliorated by the inhibition of Flt3, or Flt3 and FAK.

FAK INHIBITORS

A compound of the formula (I): where R1 or R2 is a cycle amine group and R5 is an aromatic group with a carbonyl containing substituent for use as a FAK inhibitor.