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Usage

Uses

Used in Analytical Chemistry:
4-BROMO-8-HYDROXYQUINOLINE is used as a chelating agent for the determination and quantification of various metals, especially aluminum, due to its high affinity for metal ions.
Used in Pharmaceutical Production:
4-BROMO-8-HYDROXYQUINOLINE is used as an intermediate in the synthesis of pharmaceuticals, leveraging its complexing properties to enhance the efficacy and stability of certain drugs.
Used in Agrochemicals:
In the agrochemical industry, 4-BROMO-8-HYDROXYQUINOLINE is used as a component in the development of products with antibacterial and antifungal properties, contributing to crop protection and disease management.
Used in Corrosion Inhibition:
4-BROMO-8-HYDROXYQUINOLINE is employed as a corrosion inhibitor, where its chelating ability helps to prevent the degradation of metals in various industrial settings.
Used in Fluorescent Probes for Biological Molecules:
4-BROMO-8-HYDROXYQUINOLINE is utilized as a fluorescent probe for detecting and analyzing various biological molecules, taking advantage of its fluorescent properties to enhance the sensitivity and specificity of detection methods.

Upstream product

• 103028-31-5 4-bromo-8-methoxyquinoline 
• 103862-09-5 4-bromo-8-methoxy-quinoline-2-carboxylic acid 
• 2929-14-8 4-hydroxy-8-methoxy-quinoline-2-carboxylic acid 
• 21269-34-1 4-hydroxy-8-methoxyquinoline 

Relevant academic research and scientific papers

Study on Relationship Between Fluorescence Properties and Structure of Substituted 8-Hydroxyquinoline Zinc Complexes

Organic light-emitting diodes (OLEDs) produced from 8-hydroxyquinoline metal complexes play a vital role in modern electroluminescent devices. In this manuscript, a series of 8-hydroxyquinoline derivatives were synthesized by different methods and their corresponding zinc metal complexes were prepared. The UV and fluorescence properties of the complexes were measured aiming to understand the effect of substituents at the quinoline ring on the fluorescence properties of the complexes. When the C-5 of 8-hydroxyquinoline was replaced by halogen group, the fluorescence emission wavelengths had been red-shifted, at the same time, blue-shifted of fluorescence emission wavelength was observed when the C-5 position of 8-hydroxyquinoline was substituted by electron-withdrawing group. When the C-4 position of 8-hydroxyquinolie was substituted by methyl or the C-5 position was substituted by sulfonic acid group, the corresponding zinc complexes had higher fluorescence intensity than 8-hydroxyquinolie zinc.

SUBSTITUTED QUINOLINE-4-CARBOXAMIDES AND USE THEREOF

The present application relates to novel substituted quinoline-4-carboxamides and use thereof, to processes for their preparation, to their use, alone or in combinations, for the treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for the treatment and/or prophylaxis of diseases, especially for the treatment and/or prophylaxis of cardiovascular disorders.

Improved Syntheses of Some Monohloro- and Monobromo-8-quinolinols

Procedures were developed for the preparation of the 2-, 3-, 4-, and 6-monosubstituted chloro and bromo 8-quinolinols which afforded greater yields and/or reduced the number of steps in the preparation. 100 MHz 1H-NMR spetra for the 12 possible monochloro