1394001-63-8

Basic information

• Product Name: C₁₃H₇BrFNO
• CAS NO: 1394001-63-8
• Molecular Weight: 292.107
• Mol File: 1394001-63-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₃H₇BrFNO(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₃H₇BrFNO(1394001-63-8)
• EPA Substance Registry System: C₁₃H₇BrFNO(1394001-63-8)

Safety Data

• Hazardous Substances Data: 1394001-63-8(Hazardous Substances Data)

Upstream product

• 123843-67-4 4-bromo-2,6-difluorobenzonitrile 
• 98-80-6 phenylboronic acid 

Relevant articles and documents

Synthesis of unsymmetrical biaryl ethers through nickel-promoted coupling of polyfluoroarenes with arylboronic acids and oxygen

Polyfluoro-substituted unsymmetrical biaryl ethers were synthesized via a novel Ni-catalyzed cross-coupling reaction of polyfluoroarenes with arylboronic acids and oxygen. The polyfluorinated arenes presumably captured the phenoxide intermediate efficiently, which made the oxygen-insertion proceed smoothly via the SNAr protocol. The 18O labeling experiment demonstrated that the oxygen introduced into unsymmetrical diaryl ether originated from very trace amounts of oxygen in the reaction system. A plausible mechanism was also suggested.