139404-44-7

Upstream product

• 139308-11-5 (4S)-4-<(4S,5S)-4,5-dimethoxymethyl-2-methyl-1,3-dioxolan-2-yl>-1-p-methoxyphenyl-2-azetidinone 
• 144260-89-9 (R)-4-[(2S,3R)-3-Ethyl-1-(4-methoxy-phenyl)-4-oxo-azetidin-2-yl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 146726-49-0 (4S,5S)-4,5-dimethoxymethyl-2-(N-p-methoxyphenyl)iminomethyl-2-methyl-1,3-dioxolane 
• 127940-39-0 (R)-4-{[(E)-4-Methoxy-phenylimino]-methyl}-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 141781-21-7 [(S)-2-(tert-Butyl-dimethyl-silanyloxy)-prop-(E)-ylidene]-(4-methoxy-phenyl)-amine 
• 135508-39-3 (3S,4S)-3-Benzyloxy-4-[(S)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-1-(4-methoxy-phenyl)-azetidin-2-one 
• 135508-50-8 (R)-4-[(2R,3S)-3-Benzyloxy-1-(4-methoxy-phenyl)-4-oxo-azetidin-2-yl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 135508-49-5 (3S,4R)-3-acetoxy-4-<(R)-3-(tert-butoxycarbonyl)-2,2-dimethyloxazolidin-4-yl>-1-(4-methoxyphenyl)azetidin-2-one 
• 135508-51-9 (3S,4R)-4-<(R)-3-(tert-butoxycarbonyl)-2,2-dimethyloxazolidin-4-yl>-3-methoxy-1-(4-methoxyphenyl)azetidin-2-one 
• 135508-52-0 (3S,4R)-4-<(R)-3-(tert-butoxycarbonyl)-2,2-dimethyloxazolidin-4-yl>-3-hydroxy-1-(4-methoxyphenyl)azetidin-2-one 
• 135508-42-8 (3S,4S)-4-[(S)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-3-hydroxy-1-(4-methoxy-phenyl)-azetidin-2-one 
• 135508-43-9 (S)-4-[(S)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-1-(4-methoxy-phenyl)-azetidin-2-one 
• 143658-95-1 (3R,4S)-4-<(4S,5S)-4,5-dimethoxymethyl-2-methyl-1,3-dioxolan-2-yl>-1-p-methoxyphenyl-3-ethyl-2-azetidinone 
• 135508-44-0 1-(4-methoxyphenyl)-3-ethyl-4-<1-<<(1,1-dimethylethyl)dimethylsilyl>oxy>ethyl>azetidin-2-one 

Downstream Products

• 112245-46-2 (3R,4S)-4-acetoxy-3-ethyl-1-p-methoxyphenyl-2-azetidinone 

Relevant academic research and scientific papers

Diastereoface-discrimination reaction of lithium or titanium ester enolates with a chiral imine leading to stereodivergent synthesis of β-lactams

Diastereoselective addition reaction of ester enolates to a chiral imine possessing (4S, 5S)-4,5-dimethoxymethyl-2-methyl-1,3-dioxolane ring as a chiral auxiliary is reported, in which varying metal enolates resulted in the selective formation of (4S)- or

Highly diastereoselective synthesis of β-lactams by addition of titanium enolates of 2-pyridyl thioesters to chiral imines

Addition of titanium enolates of 2-pyridyl thioesters to chiral imines derived from alkoxy aldehydes occurs with good diastereofacial control, and opens a simple access to important carbapenem antibiotics.