112245-46-2

Upstream product

• 104-94-9 4-methoxy-aniline 
• 139404-44-7 (3R,4S)-4-acetyl-3-ethyl-1-p-methoxyphenyl-2-azetidinone 
• 124156-23-6 3-ethyl-4-methoxycarbonyl-1-(4-methoxyphenyl)azetidin-2-one 
• 124156-20-3 (4-methoxyphenyl-benzylidene)-carbamic acid methyl ester 
• 119873-85-7 cis-1-p-Methoxyphenyl-3-vinyl-4-ethoxycarbonylazetidinone 
• 124156-32-7 3-Eth-(E)-ylidene-1-(4-methoxy-phenyl)-4-oxo-azetidine-2-carboxylic acid ethyl ester 
• 124156-21-4 ethyl (4-methoxyphenylimino)acetate 
• 124223-53-6 cis-1-p-anisyl-3-ethyl-4-carboxy-2-azetidinone 
• 546-67-8 lead(IV) tetraacetate 
• 112113-99-2 3-Ethyl-1-(4-methoxy-phenyl)-4-oxo-azetidine-2-carboxylic acid 
• 124156-23-6 cis-3-Ethyl-4-(methoxycarbonyl)-1-(4-methoxyphenyl)azetidin-2-one 
• 124156-30-5 Z-3-Ethylidene-4-(methoxycarbonyl)-1-(4-methoxyphenyl)azetidin-2-one 
• 124156-24-7 cis-1-p-anisyl-3-ethyl-4-carbethoxy-2-azetidinone 
• 124156-22-5 cis-1-(4-Methoxyphenyl)-3-vinyl-4-(methoxycarbonyl)-2-azetidinone 

Relevant academic research and scientific papers

Diastereoface-discrimination reaction of lithium or titanium ester enolates with a chiral imine leading to stereodivergent synthesis of β-lactams

Diastereoselective addition reaction of ester enolates to a chiral imine possessing (4S, 5S)-4,5-dimethoxymethyl-2-methyl-1,3-dioxolane ring as a chiral auxiliary is reported, in which varying metal enolates resulted in the selective formation of (4S)- or

The acid chloride-iminoester condensation: A direct approach to PS-5 and PS-6 intermediates and related compounds

The dehydrochlorination of alkanoyl chlorides with triethylamine in the presence of α-iminoesters produced 3-alkyl-4-alkoxycarbonyl β-lactams in excellent yields and high stereoselectivity.

β-Lactams via α,β-Unsaturated Acid Chlorides: Intermediates for Carbapenem Antibiotics

Stereocontrolled synthesis of α-vinyl β-lactams and their transformation to convenient intermediates for PS-5, PS-6, asparenomycin, and thienamycin are described.