1394050-90-8Relevant articles and documents
Synthesis and biological studies of novel biphenyl-3,5-dihydro-2H- thiazolopyrimidines derivatives
Maddila,Damu,Oseghe,Abafe,Venakata Rao,Lavanya
, p. 334 - 340 (2012/09/05)
A new series of ethyl 2-(4-substitutedbenzylidene)-5-(3′- (ethoxycarbonyl)biphenyl-4-yl)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a] pyrimidine-6-carboxylate derivatives (8a-j) were synthesized. The newly synthesized compounds were characterized by IR, 1H NMR, 13C NMR, LCMS mass and C, H, N analyses. All newly synthesized compounds were screened for their In vitro antioxidant activity (Scavenging of hydrogen peroxide, Scavenging of nitric oxide radical, and Lipid peroxidation inhibitory activity), antibacterial (Escheria coli, Pseudonmonas aeruginosa (gram-negative bacteria), Bacillus sub-tillis, Staphylococcus aureus (gram-positive bacteria)) and antifungal (Candida albicans Aspergillus niger) studies.