1394123-41-1

Basic information

• Product Name: C₂₁H₁₄OS
• Synonyms: C₂₁H₁₄OS
• CAS NO: 1394123-41-1
• Molecular Weight: 314.408
• Mol File: 1394123-41-1.mol

Chemical Properties

• CAS DataBase Reference: C₂₁H₁₄OS(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₁₄OS(1394123-41-1)
• EPA Substance Registry System: C₂₁H₁₄OS(1394123-41-1)

Safety Data

• Hazardous Substances Data: 1394123-41-1(Hazardous Substances Data)

Upstream product

• 98-03-3 thiophene-2-carbaldehyde 
• 171258-08-5 2-(phenylethynyl)acetophenone 
• 2142-70-3 2-iodoacetophenone 

Downstream Products

• 1394123-24-0 ethyl 4-(1-oxo-2-phenyl-1H-inden-3-yl)-3-(thiophen-2-yl)-1H-pyrrole-2-carboxylate 

Relevant articles and documents

Iodine-mediated synthesis of benzo[: A] fluorenones from yne-enones

The chalcones derived from o-alkynylacetophenones and aromatic aldehydes (yne-enones) when heated under reflux with iodine in acetic acid gave a range of benzo[a]fluorenone derivatives in moderate to good yields. The transformation involves the formation of a vinyl indenone intermediate through regioselective alkyne hydration and intramolecular aldol condensation followed by electrocyclic ring closure and aromatization.

Radical-Triggered Tandem Cyclization of 1,6-Enynes with H2O: A Way to Access Strained 1 H-Cyclopropa[ b]naph thalene-2,7-diones

A radical-triggered tandem cyclization of 1,6-enynes has been developed herein. Strained 1H-cyclopropa[b]naphthalene-2,7-diones are successfully obtained in moderate to good yields with excellent stereoselectivity. Mechanistic studies reveal a key role of water in generating a hydroxyl radical that initiates a sequential Michael addition/ring closure pathway. Importantly, the formed hydroxyl is proposed to be a good leaving group during the cyclopropane ring formation.