1394137-59-7

Basic information

• Product Name: C₁₇H₁₂F₂N₄OS
• CAS NO: 1394137-59-7
• Molecular Weight: 358.371
• Mol File: 1394137-59-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₇H₁₂F₂N₄OS(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₇H₁₂F₂N₄OS(1394137-59-7)
• EPA Substance Registry System: C₁₇H₁₂F₂N₄OS(1394137-59-7)

Safety Data

• Hazardous Substances Data: 1394137-59-7(Hazardous Substances Data)

Upstream product

• 18927-05-4 methyl (3-methoxyphenyl)acetate 
• 1798-09-0 m-methoxyphenylacetic acid 
• 34624-38-9 2-(3-methoxyphenyl)acetic hydrazide 
• 1038304-53-8 4-amino-3-(3-methoxybenzyl)-1H-1,2,4-triazole-5(4H)-thione 
• 2991-28-8 2,5-difluorobenzoic acid 

Relevant articles and documents

Synthesis, urease inhibition, antioxidant and antibacterial studies of some 4-Amino-5-aryl-3H-1,2,4-triazole-3-thiones and their 3,6-Disubstituted 1,2,4-Triazolo[3,4-b]1,3,4-thiadiazole derivatives

A new series of 4-amino-5-aryl-3H-1,2,4-triazole-3-thiones, bearing various methoxybenzyl- and methoxyphenethyl groups, was synthesized by refluxing potassium hydrazinecarbodithioate salts in dilute aqueous solution of hydrazine hydrate. These salts were formed by the reaction of acid hydrazides and carbon disulfide in methanolic potassium hydroxide solution at 0-5 °C. 4-Amino-5-aryl-3H-1,2,4-triazole-3-thiones were condensed with different substituted aromatic acids to yield 3,6-disubstituted-1,2,4-triazolo[3,4-b]1,3, 4-thiadiazoles. The structures of the synthesized compounds were characterized by infrared (IR), 1H and 13C nuclear magnetic resonance (NMR), elemental analysis and mass spectrometric (MS) studies. All the synthesized compounds were screened for their urease inhibition, antioxidant and antibacterial activities. Some compounds showed excellent urease inhibition activity, more than the standard drug. Others exhibited potent antioxidant activity. All the compounds showed significant antibacterial activities as compared to the standard drug.