1394138-02-3

Basic information

• Product Name: C₃₁H₂₇BrN₂O₂
• Synonyms: C₃₁H₂₇BrN₂O₂
• CAS NO: 1394138-02-3
• Molecular Weight: 539.472
• Mol File: 1394138-02-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₁H₂₇BrN₂O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₁H₂₇BrN₂O₂(1394138-02-3)
• EPA Substance Registry System: C₃₁H₂₇BrN₂O₂(1394138-02-3)

Safety Data

• Hazardous Substances Data: 1394138-02-3(Hazardous Substances Data)

Upstream product

• 603-76-9 1-methylindole 
• 22979-35-7 Methyl phenyldiazoacetate 
• 18467-14-6 N-(3-bromobenzylidene)-phenyl-amine 

Relevant articles and documents

Highly enantioselective trapping of zwitterionic intermediates by imines

Reactions with the unstable and highly reactive zwitterionic intermediates generated in processes catalysed by transition metals are providing new opportunities for molecular constructions. Insertion reactions involve the collapse of zwitterionic intermediates, but trapping them would allow structural elaborations that are not currently available. To synthesize complex molecules in this manner, reactive electrophiles can be used to trap the zwitterionic intermediates. Here, we describe the use of imines, activated by chiral organocatalysts, and a highly efficient integrated rhodium and chiral Brnsted acid co-catalysed process to trap zwitterionic intermediates that have been proposed previously to undergo a formal C-H insertion reaction, allowing us to obtain polyfunctionalized indole and oxindole derivatives in a single step with excellent diastereoselectivity and enantioselectivity.