139418-98-7

Basic information

• Product Name: 1-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)-5-methoxytetrahydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione (non-preferred name)
• CAS NO: 139418-98-7
• Molecular Formula: C₁₁H₁₅FN₂O₅
• Molecular Weight: 274.2456
• Mol File: 139418-98-7.mol
• Article Data: 1

Chemical Properties

• Density: 1.43g/cm³
• Refractive Index: 1.555
• CAS DataBase Reference: 1-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)-5-methoxytetrahydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione (non-preferred name)(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)-5-methoxytetrahydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione (non-preferred name)(139418-98-7)
• EPA Substance Registry System: 1-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)-5-methoxytetrahydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione (non-preferred name)(139418-98-7)

Safety Data

• Hazardous Substances Data: 139418-98-7(Hazardous Substances Data)

Usage

Chemical structure

The compound consists of a pyrimidine-2,4(1H,3H)-dione ring system attached to a tetrahydrofuran ring with a fluoro, hydroxymethyl, and methoxy substituent.

Stereochemistry

The compound has a specific stereochemistry, with the 2R, 4S, and 5R configurations at the tetrahydrofuran ring.

Functional groups

The compound contains a hydroxymethyl group, a methoxy group, and a methyl group attached to the pyrimidine ring.

Fluorination

The compound has a fluoro substituent at the 4-position of the tetrahydrofuran ring.

Pharmacological applications

The compound may have various pharmacological applications, although specific uses are not provided in the material.

Biological applications

The compound may have biological applications, although specific uses are not provided in the material.

Industrial applications

The compound may have industrial applications, although specific uses are not provided in the material.

Solubility

The solubility of the compound is not provided in the material.

Stability

The stability of the compound under various conditions is not provided in the material.

Reactivity

The reactivity of the compound with other chemicals or under different conditions is not provided in the material.

Synthesis

The synthesis method for the compound is not provided in the material.

Purity

The purity of the compound is not provided in the material.

Safety

The safety profile of the compound, including any potential hazards or precautions, is not provided in the material.

Regulatory status

The regulatory status of the compound, including any approvals or restrictions, is not provided in the material.

Upstream product

• 51247-12-2 3',5'-dideoxy-3'-fluoro-5'-iodothymidine 
• 25526-93-6 alovudine 
• 67-56-1 methanol 
• 51247-13-3 1-(3-fluoro-2,3,5-trideoxy-β-D-glycero-pent-4-enofuranosyl)thymine 

Relevant articles and documents

Synthesis and anti-HIV activity of 4'-azido- and 4'-methoxynucleosides

A series of nucleosides were synthesized in which the 4'-hydrogen was substituted with either an azido or a methoxy group. The key steps in the syntheses of the 4'-azido analogues were the stereo- and regioselective addition of iodine azide to a 4'-unsatu