139429-03-1Relevant articles and documents
Potent and systemically active aminopeptidase N inhibitors designed from active-site investigation
Fournie-Zaluski,Coric,Turcaud,Bruetschy,Lucas,Noble,Roques
, p. 1259 - 1266 (2007/10/02)
Derivatives of amino acids bearing various zinc-coordinating moieties (SH, COOH, CONHOH, and PO3H2) were synthesized and tested for their ability to inhibit aminopeptidase N (APN). Among them, β-amino thiols were found to be the most