1394290-81-3

Basic information

• Product Name: 1-methyl-4-(6,6,6-trifluorohexa-1,3-diyn-1-yl)benzene
• Synonyms: 1-methyl-4-(6,6,6-trifluorohexa-1,3-diyn-1-yl)benzene
• CAS NO: 1394290-81-3
• Molecular Weight: 222.21
• Mol File: 1394290-81-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-methyl-4-(6,6,6-trifluorohexa-1,3-diyn-1-yl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methyl-4-(6,6,6-trifluorohexa-1,3-diyn-1-yl)benzene(1394290-81-3)
• EPA Substance Registry System: 1-methyl-4-(6,6,6-trifluorohexa-1,3-diyn-1-yl)benzene(1394290-81-3)

Safety Data

• Hazardous Substances Data: 1394290-81-3(Hazardous Substances Data)

Upstream product

• 371-67-5 2,2,2-trifluorodiazoethane 
• 38177-85-4 1-(buta-1,3-diyn-1-yl)-4-methylbenzene 
• 306-83-2 1,1,1-trifluoro-2,2-dichloroethane 
• 766-97-2 4-n-methylphenylacetylene 
• 130248-74-7 1-methyl-4-[4-(trimethylsilyl)-1,3-butadiyn-1-yl]benzene 

Relevant articles and documents

Syntheses of trifluoroethylated unsymmetrical 1,3-diynes by using 1,1-dichloro-2,2,2-trifluoroethane

Copper-mediated reaction of terminal 1,3-diynes with 1,1-dichloro-2,2,2-trifluoroethane (CF3CHCl2) using ethanolamine as ligand gave trifluoroethylated unsymmetrical 1,3-diynes in moderate to good yields. The reaction were carried out under mild conditions, and were easy to operate. Aryl groups with weak electron-withdrawing group or electron-donating group, and alkyl substitutents at terminal 1,3-diynes were tolerated. Synthesis of a trifluoroethylated conjugated triyne by using this method was demonstrated. Further transformation of the trifluoroethylated unsymmetrical 1,3-diyne to provide trifluoroethyl-substituted 1,2,3-triazole and isoxazole as application examples were successfully realized.